Plasmacytoid Dendritic Cells Mediate Myocardial Ischemia/Reperfusion Injury by Secreting Type I Interferons

BACKGROUND: We previously demonstrated that ischemically injured cardiomyocytes release cell‐free DNA and HMGB1 (high mobility group box 1 protein) into circulation during reperfusion, activating proinflammatory responses and ultimately exacerbating reperfusion injury. We hypothesize that cell‐free...

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Detalles Bibliográficos
Autores principales: Lai, Lina, Zhang, Aimee, Yang, Boris, Charles, Eric J., Kron, Irving L., Yang, Zequan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475660/
https://www.ncbi.nlm.nih.gov/pubmed/34325534
http://dx.doi.org/10.1161/JAHA.121.020754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475660/
https://www.ncbi.nlm.nih.gov/pubmed/34325534
http://dx.doi.org/10.1161/JAHA.121.020754

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