Replication Stress Response Modifies Sarcomeric Cardiomyopathy Remodeling

BACKGROUND: Sarcomere gene mutations lead to cardiomyocyte hypertrophy and pathological myocardial remodeling. However, there is considerable phenotypic heterogeneity at both the cellular and the organ level, suggesting modifiers regulate the effects of these mutations. We hypothesized that sarcomer...

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Detalles Bibliográficos
Autores principales: Pal, Soumojit, Nixon, Benjamin R., Glennon, Michael S., Shridhar, Puneeth, Satterfield, Sidney L., Su, Yan Ru, Becker, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475701/
https://www.ncbi.nlm.nih.gov/pubmed/34323119
http://dx.doi.org/10.1161/JAHA.121.021768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475701/
https://www.ncbi.nlm.nih.gov/pubmed/34323119
http://dx.doi.org/10.1161/JAHA.121.021768

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