Penetrance of Severe Pulmonary Arterial Hypertension in Response to Vascular Endothelial Growth Factor Receptor 2 Blockade in a Genetically Prone Rat Model Is Reduced by Female Sex

BACKGROUND: We have previously reported important strain differences in response to SU5416 (SU, a vascular endothelial growth factor receptor 2 inhibitor) in rats and have identified a specific colony of Sprague‐Dawley rats that are hyperresponsive (SD(HR)) to SU alone and develop severe pulmonary a...

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Detalles Bibliográficos
Autores principales: Chaudhary, Ketul R., Deng, Yupu, Yang, Anli, Cober, Nicholas D., Stewart, Duncan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475703/
https://www.ncbi.nlm.nih.gov/pubmed/34315227
http://dx.doi.org/10.1161/JAHA.120.019488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475703/
https://www.ncbi.nlm.nih.gov/pubmed/34315227
http://dx.doi.org/10.1161/JAHA.120.019488

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