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HE4 Predicts Progressive Fibrosis and Cardiovascular Events in Patients With Dilated Cardiomyopathy

BACKGROUND: Cardiac fibrosis plays a crucial role in the pathogenesis of dilated cardiomyopathy (DCM). HE4 (human epididymis protein 4) is a secretory protein expressed in activated fibroblasts that exacerbates tissue fibrosis. In the present study, we investigated the clinical utility of HE4 measur...

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Detalles Bibliográficos
Autores principales: Yamamoto, Masahiro, Hanatani, Shinsuke, Araki, Satoshi, Izumiya, Yasuhiro, Yamada, Toshihiro, Nakanishi, Nobuhiro, Ishida, Toshifumi, Yamamura, Satoru, Kimura, Yuichi, Arima, Yuichiro, Nakamura, Taishi, Takashio, Seiji, Yamamoto, Eiichiro, Sakamoto, Kenji, Kaikita, Koichi, Matsushita, Kenichi, Morimoto, Sachio, Ito, Takaaki, Tsujita, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475713/
https://www.ncbi.nlm.nih.gov/pubmed/34320813
http://dx.doi.org/10.1161/JAHA.120.021069