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Chronic Distress in Male Mice Impairs Motivation Compromising Both Effort and Reward Processing With Altered Anterior Insular Cortex and Basolateral Amygdala Neural Activation

In humans and mammals, effort-based decision-making for monetary or food rewards paradigms contributes to the study of adaptive goal-directed behaviours acquired through reinforcement learning. Chronic distress modelled by repeated exposure to glucocorticoids in rodents induces suboptimal decision-m...

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Detalles Bibliográficos
Autores principales: Cabeza, Lidia, Ramadan, Bahrie, Cramoisy, Stephanie, Houdayer, Christophe, Haffen, Emmanuel, Risold, Pierre-Yves, Fellmann, Dominique, Peterschmitt, Yvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475760/
https://www.ncbi.nlm.nih.gov/pubmed/34588963
http://dx.doi.org/10.3389/fnbeh.2021.717701