Cargando…

Differential Requirement of Gata2a and Gata2b for Primitive and Definitive Myeloid Development in Zebrafish

Germline loss or mutation of one copy of the transcription factor GATA2 in humans leads to a range of clinical phenotypes affecting hematopoietic, lymphatic and vascular systems. GATA2 heterozygous mice show only a limited repertoire of the features observed in humans. Zebrafish have two copies of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Peña, Oscar A., Lubin, Alexandra, Rowell, Jasmine, Hoade, Yvette, Khokhar, Noreen, Lemmik, Hanna, Mahony, Christopher, Dace, Phoebe, Umamahesan, Chianna, Payne, Elspeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475954/
https://www.ncbi.nlm.nih.gov/pubmed/34589480
http://dx.doi.org/10.3389/fcell.2021.708113