Pixelwise H-score: A novel digital image analysis-based metric to quantify membrane biomarker expression from immunohistochemistry images

Immunohistochemistry (IHC) assays play a central role in evaluating biomarker expression in tissue sections for diagnostic and research applications. Manual scoring of IHC images, which is the current standard of practice, is known to have several shortcomings in terms of reproducibility and scalabi...

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Detalles Bibliográficos
Autores principales: Ram, Sripad, Vizcarra, Pamela, Whalen, Pamela, Deng, Shibing, Painter, C. L., Jackson-Fisher, Amy, Pirie-Shepherd, Steven, Xia, Xiaoling, Powell, Eric L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475990/
https://www.ncbi.nlm.nih.gov/pubmed/34570796
http://dx.doi.org/10.1371/journal.pone.0245638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8475990/
https://www.ncbi.nlm.nih.gov/pubmed/34570796
http://dx.doi.org/10.1371/journal.pone.0245638

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