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Metformin and sodium dichloroacetate effects on proliferation, apoptosis, and metabolic activity tested alone and in combination in a canine prostate and a bladder cancer cell line

An important approach in tumor therapy is combining substances with different action mechanisms aiming to enhance the antineoplastic effect, decrease the therapeutic dosage, and avoid resistance mechanisms. Moreover, evaluating compounds already approved for the treatment of non-neoplastic diseases...

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Detalles Bibliográficos
Autores principales: Klose, Katharina, Packeiser, Eva-Maria, Müller, Petra, Granados-Soler, José Luis, Schille, Jan Torben, Goericke-Pesch, Sandra, Kietzmann, Manfred, Murua Escobar, Hugo, Nolte, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476037/
https://www.ncbi.nlm.nih.gov/pubmed/34570803
http://dx.doi.org/10.1371/journal.pone.0257403