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Metformin and sodium dichloroacetate effects on proliferation, apoptosis, and metabolic activity tested alone and in combination in a canine prostate and a bladder cancer cell line
An important approach in tumor therapy is combining substances with different action mechanisms aiming to enhance the antineoplastic effect, decrease the therapeutic dosage, and avoid resistance mechanisms. Moreover, evaluating compounds already approved for the treatment of non-neoplastic diseases...
Autores principales: | Klose, Katharina, Packeiser, Eva-Maria, Müller, Petra, Granados-Soler, José Luis, Schille, Jan Torben, Goericke-Pesch, Sandra, Kietzmann, Manfred, Murua Escobar, Hugo, Nolte, Ingo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476037/ https://www.ncbi.nlm.nih.gov/pubmed/34570803 http://dx.doi.org/10.1371/journal.pone.0257403 |
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