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Analysis of T cell receptor clonotypes in tumor microenvironment identifies shared cancer-type-specific signatures
Despite the conventional view that a truly random V(D)J recombination process should generate a highly diverse immune repertoire, emerging reports suggest that there is a certain bias toward the generation of shared/public immune receptor chains. These studies were performed in viral diseases where...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476067/ https://www.ncbi.nlm.nih.gov/pubmed/34580764 http://dx.doi.org/10.1007/s00262-021-03047-7 |