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Analysis of T cell receptor clonotypes in tumor microenvironment identifies shared cancer-type-specific signatures

Despite the conventional view that a truly random V(D)J recombination process should generate a highly diverse immune repertoire, emerging reports suggest that there is a certain bias toward the generation of shared/public immune receptor chains. These studies were performed in viral diseases where...

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Detalles Bibliográficos
Autores principales: Teng, Yvonne H. F., Quah, Hong Sheng, Suteja, Lisda, Dias, João M. L., Mupo, Annalisa, Bashford-Rogers, Rachael J. M., Vassiliou, George S., Chua, Melvin L. K., Tan, Daniel S. W., Lim, Darren W. T., Iyer, N. Gopalakrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476067/
https://www.ncbi.nlm.nih.gov/pubmed/34580764
http://dx.doi.org/10.1007/s00262-021-03047-7