Single-molecule imaging reveals the concerted release of myosin from regulated thin filaments

Regulated thin filaments (RTFs) tightly control striated muscle contraction through calcium binding to troponin, which enables tropomyosin to expose myosin-binding sites on actin. Myosin binding holds tropomyosin in an open position, exposing more myosin-binding sites on actin, leading to cooperativ...

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Detalles Bibliográficos
Autores principales: Smith, Quentin M, Inchingolo, Alessio V, Mihailescu, Madalina-Daniela, Dai, Hongsheng, Kad, Neil M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476120/
https://www.ncbi.nlm.nih.gov/pubmed/34569933
http://dx.doi.org/10.7554/eLife.69184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476120/
https://www.ncbi.nlm.nih.gov/pubmed/34569933
http://dx.doi.org/10.7554/eLife.69184

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