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Innate immune activation by checkpoint inhibition in human patient-derived lung cancer tissues

Although Pembrolizumab-based immunotherapy has significantly improved lung cancer patient survival, many patients show variable efficacy and resistance development. A better understanding of the drug’s action is needed to improve patient outcomes. Functional heterogeneity of the tumor microenvironme...

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Detalles Bibliográficos
Autores principales: Fan, Teresa WM, Higashi, Richard M, Song, Huan, Daneshmandi, Saeed, Mahan, Angela L, Purdom, Matthew S, Bocklage, Therese J, Pittman, Thomas A, He, Daheng, Wang, Chi, Lane, Andrew N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476122/
https://www.ncbi.nlm.nih.gov/pubmed/34406120
http://dx.doi.org/10.7554/eLife.69578