Binding affinity landscapes constrain the evolution of broadly neutralizing anti-influenza antibodies

Over the past two decades, several broadly neutralizing antibodies (bnAbs) that confer protection against diverse influenza strains have been isolated. Structural and biochemical characterization of these bnAbs has provided molecular insight into how they bind distinct antigens. However, our underst...

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Detalles Bibliográficos
Autores principales: Phillips, Angela M, Lawrence, Katherine R, Moulana, Alief, Dupic, Thomas, Chang, Jeffrey, Johnson, Milo S, Cvijovic, Ivana, Mora, Thierry, Walczak, Aleksandra M, Desai, Michael M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476123/
https://www.ncbi.nlm.nih.gov/pubmed/34491198
http://dx.doi.org/10.7554/eLife.71393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476123/
https://www.ncbi.nlm.nih.gov/pubmed/34491198
http://dx.doi.org/10.7554/eLife.71393

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