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Inducible and reversible inhibition of miRNA-mediated gene repression in vivo

Although virtually all gene networks are predicted to be controlled by miRNAs, the contribution of this important layer of gene regulation to tissue homeostasis in adult animals remains unclear. Gain and loss-of-function experiments have provided key insights into the specific function of individual...

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Detalles Bibliográficos
Autores principales: La Rocca, Gaspare, King, Bryan, Shui, Bing, Li, Xiaoyi, Zhang, Minsi, Akat, Kemal M, Ogrodowski, Paul, Mastroleo, Chiara, Chen, Kevin, Cavalieri, Vincenzo, Ma, Yilun, Anelli, Viviana, Betel, Doron, Vidigal, Joana, Tuschl, Thomas, Meister, Gunter, Thompson, Craig B, Lindsten, Tullia, Haigis, Kevin, Ventura, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476124/
https://www.ncbi.nlm.nih.gov/pubmed/34463618
http://dx.doi.org/10.7554/eLife.70948