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Dissecting the Fitness Costs of Complex Mutations

The fitness cost of complex pleiotropic mutations is generally difficult to assess. On the one hand, it is necessary to identify which molecular properties are directly altered by the mutation. On the other, this alteration modifies the activity of many genetic targets with uncertain consequences. H...

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Detalles Bibliográficos
Autores principales: Yubero, Pablo, Poyatos, Juan F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476139/
https://www.ncbi.nlm.nih.gov/pubmed/34175930
http://dx.doi.org/10.1093/molbev/msab193