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Inferring Genome-Wide Correlations of Mutation Fitness Effects between Populations

The effect of a mutation on fitness may differ between populations depending on environmental and genetic context, but little is known about the factors that underlie such differences. To quantify genome-wide correlations in mutation fitness effects, we developed a novel concept called a joint distr...

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Detalles Bibliográficos
Autores principales: Huang, Xin, Fortier, Alyssa Lyn, Coffman, Alec J, Struck, Travis J, Irby, Megan N, James, Jennifer E, León-Burguete, José E, Ragsdale, Aaron P, Gutenkunst, Ryan N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476148/
https://www.ncbi.nlm.nih.gov/pubmed/34043790
http://dx.doi.org/10.1093/molbev/msab162