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Unique Pathogen Peptidomes Facilitate Pathogen-Specific Selection and Specialization of MHC Alleles
A key component of pathogen-specific adaptive immunity in vertebrates is the presentation of pathogen-derived antigenic peptides by major histocompatibility complex (MHC) molecules. The excessive polymorphism observed at MHC genes is widely presumed to result from the need to recognize diverse patho...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476153/ https://www.ncbi.nlm.nih.gov/pubmed/34110412 http://dx.doi.org/10.1093/molbev/msab176 |