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Biomolecular condensates amplify mRNA decapping by biasing enzyme conformation

Cells organize biochemical processes into biological condensates. P-bodies are cytoplasmic condensates enriched in enzymes important for mRNA degradation and have been identified as sites of both storage and decay. How these opposing outcomes can be achieved in condensates remains unresolved. mRNA d...

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Detalles Bibliográficos
Autores principales: Tibble, Ryan W., Depaix, Anaïs, Kowalska, Joanna, Jemielity, Jacek, Gross, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476181/
https://www.ncbi.nlm.nih.gov/pubmed/33767388
http://dx.doi.org/10.1038/s41589-021-00774-x