TMBIM6 regulates redox-associated posttranslational modifications of IRE1α and ER stress response failure in aging mice and humans

Age-associated persistent ER stress is the result of declining chaperone systems of the ER that reduces cellular functions, induces apoptosis, and leads to age-related diseases. This study investigated the previously unknown regulatory mechanism of TMBIM6 during age-associated hepatic abnormalities....

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Detalles Bibliográficos
Autores principales: Bhattarai, Kashi Raj, Kim, Hyun-Kyoung, Chaudhary, Manoj, Ur Rashid, Mohammad Mamun, Kim, Jisun, Kim, Hyung-Ryong, Chae, Han-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476450/
https://www.ncbi.nlm.nih.gov/pubmed/34562874
http://dx.doi.org/10.1016/j.redox.2021.102128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476450/
https://www.ncbi.nlm.nih.gov/pubmed/34562874
http://dx.doi.org/10.1016/j.redox.2021.102128

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