Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control

Obesity induces skeletal muscle dysfunction. The pathogenesis of which appears to substantially involve mitochondrial dysfunction, arising from impaired quality control. Exercise is a major therapeutic strategy against muscle dysfunction. Trimetazidine, a partial inhibitor of lipid oxidation, has be...

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Detalles Bibliográficos
Autores principales: Zhang, Wenliang, You, Baiyang, Qi, Dake, Qiu, Ling, Ripley-Gonzalez, Jeffrey W., Zheng, Fan, Fu, Siqian, Li, Cui, Dun, Yaoshan, Liu, Suixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476493/
https://www.ncbi.nlm.nih.gov/pubmed/34580406
http://dx.doi.org/10.1038/s41598-021-98771-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476493/
https://www.ncbi.nlm.nih.gov/pubmed/34580406
http://dx.doi.org/10.1038/s41598-021-98771-6

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