Development and characterization of a DNA aptamer for MLL-AF9 expressing acute myeloid leukemia cells using whole cell-SELEX

Current classes of cancer therapeutics have negative side effects stemming from off-target cytotoxicity. One way to avoid this would be to use a drug delivery system decorated with targeting moieties, such as an aptamer, if a targeted aptamer is available. In this study, aptamers were selected again...

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Detalles Bibliográficos
Autores principales: Earnest, Kaylin G., McConnell, Erin M., Hassan, Eman M., Wunderlich, Mark, Hosseinpour, Bahareh, Bono, Bianca S., Chee, Melissa J., Mulloy, James C., Willmore, William G., DeRosa, Maria C., Merino, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476576/
https://www.ncbi.nlm.nih.gov/pubmed/34580387
http://dx.doi.org/10.1038/s41598-021-98676-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476576/
https://www.ncbi.nlm.nih.gov/pubmed/34580387
http://dx.doi.org/10.1038/s41598-021-98676-4

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