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Development and characterization of a DNA aptamer for MLL-AF9 expressing acute myeloid leukemia cells using whole cell-SELEX
Current classes of cancer therapeutics have negative side effects stemming from off-target cytotoxicity. One way to avoid this would be to use a drug delivery system decorated with targeting moieties, such as an aptamer, if a targeted aptamer is available. In this study, aptamers were selected again...
Autores principales: | Earnest, Kaylin G., McConnell, Erin M., Hassan, Eman M., Wunderlich, Mark, Hosseinpour, Bahareh, Bono, Bianca S., Chee, Melissa J., Mulloy, James C., Willmore, William G., DeRosa, Maria C., Merino, Edward J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476576/ https://www.ncbi.nlm.nih.gov/pubmed/34580387 http://dx.doi.org/10.1038/s41598-021-98676-4 |
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