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Direct access to spirocycles by Pd/WingPhos-catalyzed enantioselective cycloaddition of 1,3-enynes

Spirocycles play an important role in drug discovery and development. The direct, catalytic, and enantioselective synthesis of spirocycles from readily available starting materials and in an atom economic manner remains a highly sought-after task in organic synthesis. Herein, an enantioselective Pd-...

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Detalles Bibliográficos
Autores principales: Li, Long, Wang, Shan, Luo, Pengfei, Wang, Ran, Wang, Zheng, Li, Xiaoguang, Deng, Yuhua, Peng, Fangzhi, Shao, Zhihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476582/
https://www.ncbi.nlm.nih.gov/pubmed/34580311
http://dx.doi.org/10.1038/s41467-021-25981-x