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Mapping the glycosyltransferase fold landscape using interpretable deep learning

Glycosyltransferases (GTs) play fundamental roles in nearly all cellular processes through the biosynthesis of complex carbohydrates and glycosylation of diverse protein and small molecule substrates. The extensive structural and functional diversification of GTs presents a major challenge in mappin...

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Detalles Bibliográficos
Autores principales: Taujale, Rahil, Zhou, Zhongliang, Yeung, Wayland, Moremen, Kelley W., Li, Sheng, Kannan, Natarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476585/
https://www.ncbi.nlm.nih.gov/pubmed/34580305
http://dx.doi.org/10.1038/s41467-021-25975-9