Cargando…

METTL14 aggravates podocyte injury and glomerulopathy progression through N(6)-methyladenosine-dependent downregulating of Sirt1

Podocytes are known to play a determining role in the progression of proteinuric kidney disease. N(6)-methyladenosine (m6A), as the most abundant chemical modification in eukaryotic mRNA, has been reported to participate in various pathological processes. However, its role in podocyte injury remains...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Zhihui, Liu, Hong, Song, Nana, Liang, Yiran, Zhu, Jiaming, Chen, Jing, Ning, Yichun, Hu, Jiachang, Fang, Yi, Teng, Jie, Zou, Jianzhou, Dai, Yan, Ding, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476597/
https://www.ncbi.nlm.nih.gov/pubmed/34580283
http://dx.doi.org/10.1038/s41419-021-04156-y