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Sarcopenia-derived exosomal micro-RNA 16-5p disturbs cardio-repair via a pro-apoptotic mechanism in myocardial infarction in mice

Sarcopenia is a pathophysiological malfunction induced by skeletal muscle atrophy. Several studies reported an association between sarcopenia-induced cardiac cachexia and poor prognosis in heart disease. However, due to lack of an established animal models, the underlying mechanism of disturbed card...

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Detalles Bibliográficos
Autores principales: Hayasaka, Taiki, Takehara, Naofumi, Aonuma, Tatsuya, Kano, Kohei, Horiuchi, Kiwamu, Nakagawa, Naoki, Tanaka, Hiroki, Kawabe, Jun-ichi, Hasebe, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476608/
https://www.ncbi.nlm.nih.gov/pubmed/34580402
http://dx.doi.org/10.1038/s41598-021-98761-8