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Pathway of Hsp70 interactions at the ribosome

In eukaryotes, an Hsp70 molecular chaperone triad assists folding of nascent chains emerging from the ribosome tunnel. In fungi, the triad consists of canonical Hsp70 Ssb, atypical Hsp70 Ssz1 and J-domain protein cochaperone Zuo1. Zuo1 binds the ribosome at the tunnel exit. Zuo1 also binds Ssz1, tet...

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Detalles Bibliográficos
Autores principales: Lee, Kanghyun, Ziegelhoffer, Thomas, Delewski, Wojciech, Berger, Scott E., Sabat, Grzegorz, Craig, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476630/
https://www.ncbi.nlm.nih.gov/pubmed/34580293
http://dx.doi.org/10.1038/s41467-021-25930-8