USP7 facilitates SMAD3 autoregulation to repress cancer progression in p53-deficient lung cancer

USP7, one of the most abundant ubiquitin-specific proteases (USP), plays multifaceted roles in many cellular events, including oncogenic pathways. Accumulated studies have suggested that USP7, through modulating the MDM2/MDMX-p53 pathway, is a promising target for cancer treatment; however, little i...

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Detalles Bibliográficos
Autores principales: Huang, Yu-Ting, Cheng, An-Chieh, Tang, Hui-Chi, Huang, Guo-Cheng, Cai, Ling, Lin, Ta-Hsien, Wu, Kou-Juey, Tseng, Ping-Hui, Wang, Greg G., Chen, Wei-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476631/
https://www.ncbi.nlm.nih.gov/pubmed/34580281
http://dx.doi.org/10.1038/s41419-021-04176-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476631/
https://www.ncbi.nlm.nih.gov/pubmed/34580281
http://dx.doi.org/10.1038/s41419-021-04176-8

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