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USP7 facilitates SMAD3 autoregulation to repress cancer progression in p53-deficient lung cancer
USP7, one of the most abundant ubiquitin-specific proteases (USP), plays multifaceted roles in many cellular events, including oncogenic pathways. Accumulated studies have suggested that USP7, through modulating the MDM2/MDMX-p53 pathway, is a promising target for cancer treatment; however, little i...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476631/ https://www.ncbi.nlm.nih.gov/pubmed/34580281 http://dx.doi.org/10.1038/s41419-021-04176-8 |