Cargando…

The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells

Fluorizoline is a prohibitin-binding compound that triggers apoptosis in several cell lines from murine and human origin, as well as in primary cells from hematologic malignancies by inducing the integrated stress response and ER stress. Recently, it was described that PHB (Prohibitin) 1 and 2 are c...

Descripción completa

Detalles Bibliográficos
Autores principales: Núñez-Vázquez, Sonia, Saura-Esteller, José, Sánchez-Vera, Ismael, Guilbaud, Emma, Cosialls, Ana M., Pons, Gabriel, Ricci, Jean-Ehrland, Iglesias-Serret, Daniel, Marchetti, Sandrine, Gil, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476632/
https://www.ncbi.nlm.nih.gov/pubmed/34580273
http://dx.doi.org/10.1038/s41389-021-00352-9