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Sleeping ribosomes: Bacterial signaling triggers RaiA mediated persistence to aminoglycosides

Indole is a molecule proposed to be involved in bacterial signaling. We find that indole secretion is induced by sublethal tobramycin concentrations and increases persistence to aminoglycosides in V. cholerae. Indole transcriptomics showed increased expression of raiA, a ribosome associated factor....

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Detalles Bibliográficos
Autores principales: Lang, Manon, Krin, Evelyne, Korlowski, Chloé, Sismeiro, Odile, Varet, Hugo, Coppée, Jean-Yves, Mazel, Didier, Baharoglu, Zeynep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476650/
https://www.ncbi.nlm.nih.gov/pubmed/34611612
http://dx.doi.org/10.1016/j.isci.2021.103128