Quantitative analysis of genome packaging in recombinant AAV vectors by charge detection mass spectrometry

Recombinant adeno-associated virus (rAAV) has emerged as an important gene therapy vector with many clinical trials currently in progress. Analytical characterization and quantitation of particle content remain challenges in both the development and production of rAAV vectors. In this study, charge...

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Detalles Bibliográficos
Autores principales: Barnes, Lauren F., Draper, Benjamin E., Chen, Yu-Ting, Powers, Thomas W., Jarrold, Martin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476707/
https://www.ncbi.nlm.nih.gov/pubmed/34631929
http://dx.doi.org/10.1016/j.omtm.2021.08.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476707/
https://www.ncbi.nlm.nih.gov/pubmed/34631929
http://dx.doi.org/10.1016/j.omtm.2021.08.002

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