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Mouse Models of Antigen Presentation in Hematopoietic Stem Cell Transplantation

Allogeneic stem cell transplantation (alloSCT) is a curative therapy for hematopoietic malignancies. The therapeutic effect relies on donor T cells and NK cells to recognize and eliminate malignant cells, known as the graft-versus-leukemia (GVL) effect. However, off target immune pathology, known as...

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Detalles Bibliográficos
Autores principales: Koyama, Motoko, Hill, Geoffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476754/
https://www.ncbi.nlm.nih.gov/pubmed/34594330
http://dx.doi.org/10.3389/fimmu.2021.715893