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dCubilin- or dAMN-mediated protein reabsorption in Drosophila nephrocytes modulates longevity

Aging is a multifaceted process regulated by multiple cellular pathways, including the proteostasis network. Pharmacological or genetic enhancement of the intracellular proteostasis network extends lifespan and prevents age-related diseases. However, how proteostasis is regulated in different tissue...

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Detalles Bibliográficos
Autores principales: Feng, Xiaoming, Hong, Xizhen, Fan, Qiuxia, Chen, Liting, Li, Jing, Deng, Juan, Gong, Siqiao, Hou, Fan Fan, Zhang, Fujian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476815/
https://www.ncbi.nlm.nih.gov/pubmed/34437681
http://dx.doi.org/10.1242/dmm.047464