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dCubilin- or dAMN-mediated protein reabsorption in Drosophila nephrocytes modulates longevity
Aging is a multifaceted process regulated by multiple cellular pathways, including the proteostasis network. Pharmacological or genetic enhancement of the intracellular proteostasis network extends lifespan and prevents age-related diseases. However, how proteostasis is regulated in different tissue...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476815/ https://www.ncbi.nlm.nih.gov/pubmed/34437681 http://dx.doi.org/10.1242/dmm.047464 |