Cargando…

Emotional behavior and brain anatomy of the mdx52 mouse model of Duchenne muscular dystrophy

The exon-52-deleted mdx52 mouse is a critical model of Duchenne muscular dystrophy (DMD), as it features a deletion in a hotspot region of the DMD gene, frequently mutated in patients. Deletion of exon 52 impedes expression of several brain dystrophins (Dp427, Dp260 and Dp140), thus providing a key...

Descripción completa

Detalles Bibliográficos
Autores principales: Saoudi, Amel, Zarrouki, Faouzi, Sebrié, Catherine, Izabelle, Charlotte, Goyenvalle, Aurélie, Vaillend, Cyrille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476816/
https://www.ncbi.nlm.nih.gov/pubmed/34546327
http://dx.doi.org/10.1242/dmm.049028