A mouse model of brittle cornea syndrome caused by mutation in Zfp469

Brittle cornea syndrome (BCS) is a rare recessive condition characterised by extreme thinning of the cornea and sclera. BCS results from loss-of-function mutations in the poorly understood genes ZNF469 or PRDM5. In order to determine the function of ZNF469 and to elucidate pathogenic mechanisms, we...

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Detalles Bibliográficos
Autores principales: Stanton, Chloe M., Findlay, Amy S., Drake, Camilla, Mustafa, Mohammad Z., Gautier, Philippe, McKie, Lisa, Jackson, Ian J., Vitart, Veronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476817/
https://www.ncbi.nlm.nih.gov/pubmed/34368841
http://dx.doi.org/10.1242/dmm.049175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476817/
https://www.ncbi.nlm.nih.gov/pubmed/34368841
http://dx.doi.org/10.1242/dmm.049175

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