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Uncovering and Engineering a Mini-Regulatory Network of the TetR-Family Regulator SACE_0303 for Yield Improvement of Erythromycin in Saccharopolyspora erythraea

Erythromycins produced by Saccharopolyspora erythraea have broad-spectrum antibacterial activities. Recently, several TetR-family transcriptional regulators (TFRs) were identified to control erythromycin production by multiplex control modes; however, their regulatory network remains poorly understo...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Khan, Sabir, Wu, Panpan, Li, Bowen, Liu, Lanlan, Ni, Jingshu, Zhang, Hongxia, Chen, Ketao, Wu, Hang, Zhang, Buchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476842/
https://www.ncbi.nlm.nih.gov/pubmed/34595157
http://dx.doi.org/10.3389/fbioe.2021.692901