Organic Anion Transporting Polypeptide 2B1 (OATP2B1) Genetic Variants: In Vitro Functional Characterization and Association With Circulating Concentrations of Endogenous Substrates

Organic anion transporting polypeptide 2B1 (OATP2B1, gene SLCO2B1) is an uptake transporter that is thought to determine drug disposition and in particular, the oral absorption of medications. At present, the clinical relevance of SLCO2B1 genetic variation on pharmacokinetics is poorly understood. W...

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Detalles Bibliográficos
Autores principales: Medwid, Samantha, Price, Hayley R., Taylor, Daniel P., Mailloux, Jaymie, Schwarz, Ute I., Kim, Richard B., Tirona, Rommel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476882/
https://www.ncbi.nlm.nih.gov/pubmed/34594217
http://dx.doi.org/10.3389/fphar.2021.713567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476882/
https://www.ncbi.nlm.nih.gov/pubmed/34594217
http://dx.doi.org/10.3389/fphar.2021.713567

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