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B-Cell RANKL Contributes to Pathogen-Induced Alveolar Bone Loss in an Experimental Periodontitis Mouse Model

Periodontitis is a bacterially-induced inflammatory disease that leads to tooth loss. It results from the damaging effects of a dysregulated immune response, mediated largely by neutrophils, macrophages, T cells and B cells, on the tooth-supporting tissues including the alveolar bone. Specifically,...

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Detalles Bibliográficos
Autores principales: Settem, Rajendra P., Honma, Kiyonobu, Chinthamani, Sreedevi, Kawai, Toshihisa, Sharma, Ashu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476884/
https://www.ncbi.nlm.nih.gov/pubmed/34594237
http://dx.doi.org/10.3389/fphys.2021.722859