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Lamin A/C Mechanosensor Drives Tumor Cell Aggressiveness and Adhesion on Substrates With Tissue-Specific Elasticity

Besides its structural properties in the nucleoskeleton, Lamin A/C is a mechanosensor protein involved in perceiving the elasticity of the extracellular matrix. In this study we provide evidence about Lamin A/C-mediated regulation of osteosarcoma cell adhesion and spreading on substrates with tissue...

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Detalles Bibliográficos
Autores principales: Urciuoli, Enrica, D’Oria, Valentina, Petrini, Stefania, Peruzzi, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476891/
https://www.ncbi.nlm.nih.gov/pubmed/34595168
http://dx.doi.org/10.3389/fcell.2021.712377