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Transcriptome Analyses Identify a Metabolic Gene Signature Indicative of Antitumor Immunosuppression of EGFR Wild Type Lung Cancers With Low PD-L1 Expression

PURPOSE: With the development and application of targeted therapies like tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs), non-small cell lung cancer (NSCLC) patients have achieved remarkable survival benefits in recent years. However, epidermal growth factor receptor (EGFR)...

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Detalles Bibliográficos
Autores principales: Wang, Min, Zhu, Jie, Zhao, Fang, Xiao, Jiani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476909/
https://www.ncbi.nlm.nih.gov/pubmed/34595103
http://dx.doi.org/10.3389/fonc.2021.643503