Validation, Optimization, and Application of the Zebrafish Developmental Toxicity Assay for Pharmaceuticals Under the ICH S5(R3) Guideline

The zebrafish as an alternative animal model for developmental toxicity testing has been extensively investigated, but its assay protocol was not harmonized yet. This study has validated and optimized the zebrafish developmental toxicity assay previously reported by multiple inter-laboratory studies...

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Detalles Bibliográficos
Autores principales: Song, Yi-Sheng, Dai, Ming-Zhu, Zhu, Chen-Xia, Huang, Yan-Feng, Liu, Jing, Zhang, Cheng-Da, Xie, Feng, Peng, Yi, Zhang, Yong, Li, Chun-Qi, Zhang, Li-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476914/
https://www.ncbi.nlm.nih.gov/pubmed/34595173
http://dx.doi.org/10.3389/fcell.2021.721130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476914/
https://www.ncbi.nlm.nih.gov/pubmed/34595173
http://dx.doi.org/10.3389/fcell.2021.721130

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