Suppression of CPSF6 Enhances Apoptosis Through Alternative Polyadenylation-Mediated Shortening of the VHL 3′UTR in Gastric Cancer Cells

Alternative polyadenylation (APA) is an important RNA post-transcriptional process, which can generate diverse mRNA isoforms. Increasing evidence shows that APA is involved in cell self-renewal, development, immunity, and cancer. CPSF6 is one of the core proteins of CFIm complex and can modulate the...

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Detalles Bibliográficos
Autores principales: Shi, Xinglong, Ding, Keshuo, Zhao, Qiang, Li, Pengxiao, Kang, Yani, Tan, Sheng, Sun, Jielin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477001/
https://www.ncbi.nlm.nih.gov/pubmed/34594359
http://dx.doi.org/10.3389/fgene.2021.707644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477001/
https://www.ncbi.nlm.nih.gov/pubmed/34594359
http://dx.doi.org/10.3389/fgene.2021.707644

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