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Suppression of CPSF6 Enhances Apoptosis Through Alternative Polyadenylation-Mediated Shortening of the VHL 3′UTR in Gastric Cancer Cells
Alternative polyadenylation (APA) is an important RNA post-transcriptional process, which can generate diverse mRNA isoforms. Increasing evidence shows that APA is involved in cell self-renewal, development, immunity, and cancer. CPSF6 is one of the core proteins of CFIm complex and can modulate the...
Autores principales: | Shi, Xinglong, Ding, Keshuo, Zhao, Qiang, Li, Pengxiao, Kang, Yani, Tan, Sheng, Sun, Jielin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477001/ https://www.ncbi.nlm.nih.gov/pubmed/34594359 http://dx.doi.org/10.3389/fgene.2021.707644 |
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