Early Chronic Memantine Treatment-Induced Transcriptomic Changes in Wild-Type and Shank2-Mutant Mice

Shank2 is an excitatory postsynaptic scaffolding protein strongly implicated in autism spectrum disorders (ASDs). Shank2-mutant mice with a homozygous deletion of exons 6 and 7 (Shank2-KO mice) show decreased NMDA receptor (NMDAR) function and autistic-like behaviors at juvenile [∼postnatal day (P21...

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Detalles Bibliográficos
Autores principales: Yoo, Ye-Eun, Lee, Seungjoon, Kim, Woohyun, Kim, Hyosang, Chung, Changuk, Ha, Seungmin, Park, Jinsu, Chung, Yeonseung, Kang, Hyojin, Kim, Eunjoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477010/
https://www.ncbi.nlm.nih.gov/pubmed/34594187
http://dx.doi.org/10.3389/fnmol.2021.712576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477010/
https://www.ncbi.nlm.nih.gov/pubmed/34594187
http://dx.doi.org/10.3389/fnmol.2021.712576

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