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Arbutin Ameliorates Murine Colitis by Inhibiting JAK2 Signaling Pathway

Background and objective: Abnormal activation of Janus kinase 2 (JAK2) promotes the pathogenesis and progress of inflammatory bowel disease (IBD) by stimulating the cytokine traffic. Based on docking studies, arbutin, a natural product extracted from a traditional medicinal plant bearberry, was foun...

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Detalles Bibliográficos
Autores principales: Wang, Liang, Feng, Yuntao, Wang, Jianwen, Luo, Tenglong, Wang, Xinyue, Wu, Mengze, Wang, Runxia, Chen, Dapeng, Li, Jiyan, Wang, Jingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477021/
https://www.ncbi.nlm.nih.gov/pubmed/34594215
http://dx.doi.org/10.3389/fphar.2021.683818