Cargando…

miR-125a-5p reverses epithelial-mesenchymal transition and restores drug sensitivity by negatively regulating TAFAZZIN signaling in breast cancer

MicroRNA (miR)-125a-5p represses tafazzin phospholipid-lysophospholipid transacylases (TAFAZZIN) expression and inhibits the epithelial-mesenchymal transition (EMT) of ovarian cancer cells. EMT was found to have a crucial role in the acquisition of chemoresistance. Thus, the present study aimed to d...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Dongmei, Chen, Limei, Zhang, Xiaofang, Wang, Yanhua, Huang, Chuansheng, Li, Jianglong, He, Feilong, He, Wenxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477177/
https://www.ncbi.nlm.nih.gov/pubmed/34549308
http://dx.doi.org/10.3892/mmr.2021.12452