Synthesis, conformation and Hirshfeld surface analysis of benzoxazole methyl ester as a versatile building block for heterocycles

Solventless cyclocondensation of 2-aminothiophenol with thiourea afforded the benzo[d]oxazole-2-thiol (3a) capable of existing also in the tautomeric form benzo[d]oxazole-2(3H)-thione (3b). Acylation with methyl chloroacetate in dry ethanol in absence of any base or catalyst selectively afforded the...

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Detalles Bibliográficos
Autores principales: Saeed, Aamer, Shabir, Ghulam, Hökelek, Tuncer, Flörke, Ülrich, Erben, Mauricio F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477190/
https://www.ncbi.nlm.nih.gov/pubmed/34611565
http://dx.doi.org/10.1016/j.heliyon.2021.e08042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477190/
https://www.ncbi.nlm.nih.gov/pubmed/34611565
http://dx.doi.org/10.1016/j.heliyon.2021.e08042

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