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Dynamic interplay of two molecular switches enabled by the MEK1/2–ERK1/2 and IL-6–STAT3 signaling axes controls epithelial cell migration in response to growth factors

Cell migration is an essential physiological process, and aberrant migration of epithelial cells underlies many pathological conditions. However, the molecular mechanisms governing cell migration are not fully understood. We report here that growth factor–induced epithelial cell migration is critica...

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Detalles Bibliográficos
Autores principales: Qin, Lyugao, Cao, Xuan, Kaneko, Tomonori, Voss, Courtney, Liu, Xuguang, Wang, Guoping, Li, Shawn S.-C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477194/
https://www.ncbi.nlm.nih.gov/pubmed/34480897
http://dx.doi.org/10.1016/j.jbc.2021.101161