No evidence of neuronal damage as measured by neurofilament light chain in a HIV cure study utilising a kick-and-kill approach

OBJECTIVE: HIV-remission strategies including kick-and-kill could induce viral transcription and immune-activation in the central nervous system, potentially causing neuronal injury. We investigated the impact of kick-and-kill on plasma neurofilament light (NfL), a marker of neuro-axonal injury, in...

Descripción completa

Detalles Bibliográficos
Autores principales: Alagaratnam, Jasmini, Stöhr, Wolfgang, Toombs, Jamie, Heslegrave, Amanda, Zetterberg, Henrik, Gisslén, Magnus, Pett, Sarah, Nelson, Mark, Clarke, Amanda, Nwokolo, Nneka, Johnson, Margaret A., Khan, Maryam, Hanke, Tomas, Kopycinski, Jakub, Dorrell, Lucy, Fox, Julie, Kinloch, Sabine, Underwood, Jonathan, Pace, Matthew, Frater, John, Winston, Alan, Fidler, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477217/
https://www.ncbi.nlm.nih.gov/pubmed/34611495
http://dx.doi.org/10.1016/j.jve.2021.100056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8477217/
https://www.ncbi.nlm.nih.gov/pubmed/34611495
http://dx.doi.org/10.1016/j.jve.2021.100056

Ejemplares similares